Purchase Bactrim (Sulfamethoxazole/Trimethoprim) tablets online on PrimCareIT

How and where to order Bactrim, Septra, Co-Trimoxazole (Sulfamethoxazole/Trimethoprim) 400/80 mg, 800/160 mg tablets online:



Prices: from $0.27 per pill

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Forms: 400/80 mg, 800/160 mg tablets

Quantity: 20-360 pills

Type: Bactrim, Septra, Co-Trimoxazole generic

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Sulfamethoxazole with Trimethoprim (trade names include Bactrim, Septra, Co-Trimoxazole, Bactrim-DS, Septra-DS, Apo-Sulfatrim, Biseptol, Bactrim-F, Biseptrim, Cotrim, Cotrimoxazol, Eusaprim Forte, Novo-Trimel DS, Sepmax, Septrin, SMZ-TMP, Sulfatrim, Trimeth / Sulfa, Cotrimoxazole, Bactrim Forte) is a combined antibacterial medication from "sulfonamides and trimethoprim" pharmacological group. This medicine is used to treat various bacterial infections such as respiratory tract, renal and urinary tract, gastrointestinal tract, skin and wound, eye and ear infections, inclusion conjunctivitis, otitis media, septicaemias, travelers' diarrhea, cholera, pneumocystis pneumonia in people with HIV/AIDS, malaria, toxoplasmosis, trachoma, in veterinary, and other infections caused by sensitive organisms. It works by killing sensitive bacteria.

Trimethoprim and Sulfamethoxazole (Bactrim, Septra) tablets

Related medications:

  • Amoxicillin (Amoxil)
  • Amoxicillin, Clavulanate Potassium (Augmentin)
  • Azithromycin (Zithromax)
  • Cefaclor (Ceclor)
  • Cefadroxil (Duricef)
  • Chloramphenicol (Chloromycetin)
  • Ciprofloxacin (Cipro)
  • Clarithromycin (Biaxin)
  • Clindamycin (Cleocin)
  • Cycloserine (Seromycin)
  • Doxycycline (Vibramycin)
  • Erythromycin (Ilosone)
  • Ethionamide (Trecator-SC)
  • Levofloxacin (Levaquin)
  • Linezolid (Zyvox)
  • Metronidazole (Flagyl)
  • Minocycline (Minocin)
  • Moxifloxacin (Avelox)
  • Nalidixic Acid (Neggram)
  • Nitrofurantoin (Furadantin)
  • Norfloxacin (Noroxin)
  • Ofloxacin (Floxin)
  • Roxithromycin (Rulide)
  • Sulfadiazine, Tetroxoprim (Tibirox)
  • Sulfadiazine, Trimethoprim (Triglobe)
  • Sulfamerazine, Trimethoprim (Berlocombin)
  • Sulfamethazine, Trimethoprim (Trimerazin)
  • Sulfametrole, Trimethoprim (Lidaprim)
  • Sulfamoxole, Trimethoprim (Supristol)
  • Tetracycline (Sumycin)

    Pharmacological and medical categories:

  • Anti infective drugs
  • Antibacterial combinations
  • Antibiotics
  • Combined sulfonamides
  • Topical sulfonamides used in the treatment of dermatological diseases
  • Veterinary, pet meds

    ATC codes:

  • J - Antiinfectives for systemic use
  • J01 - Antibacterials for systemic use
  • J01E - Sulfonamides and trimethoprim
  • J01EE - Combinations of sulfonamides and trimethoprim, incl. derivatives
  • J01EE01 - Sulfamethoxazole and trimethoprim

    ICD-10 codes:

  • Ill-defined intestinal infections - 009
  • Infectious diarrhea - 009.2
  • Cholera - A00
  • Typhoid and paratyphoid fevers - A01
  • Other salmonella infections - A02
  • Shigellosis - A03
  • Other bacterial intestinal infections - A04
  • Diarrhoea and gastroenteritis of presumed infectious origin - A09
  • Brucellosis - A23
  • Scarlet fever - A38
  • Meningococcal infection - A39
  • Streptococcal septicaemia - A40
  • Other septicaemia - A41
  • Erysipelas - A46
  • Gonococcal infection - A54
  • Trachoma - A71
  • Other diseases caused by chlamydiae - A74
  • Chlamydial conjunctivitis - A74.0
  • Plasmodium falciparum malaria - B50
  • Plasmodium vivax malaria - B51
  • Plasmodium malariae malaria - B52
  • Other specified malaria - B53
  • Unspecified malaria - B54
  • Toxoplasmosis - B58
  • Pneumocystosis - B59+
  • Bacterial meningitis, not elsewhere classified - G00
  • Intracranial and intraspinal abscess and granuloma - G06
  • Suppurative and unspecified otitis media - H66
  • Acute pharyngitis - J02
  • Acute laryngitis and tracheitis - J04
  • Pneumonia due to Haemophilus influenzae - J14
  • Bacterial pneumonia, not elsewhere classified - J15
  • Acute bronchitis - J20
  • Acute bronchiolitis - J21
  • Chronic sinusitis - J32
  • Chronic diseases of tonsils and adenoids - J35
  • Chronic laryngitis and laryngotracheitis - J37
  • Unspecified chronic bronchitis - J42
  • Bronchiectasis - J47
  • Cholecystitis - K81
  • Other diseases of biliary tract - K83
  • Impetigo - L01
  • Cutaneous abscess, furuncle and carbuncle - L02
  • Cellulitis - L03
  • Other local infections of skin and subcutaneous tissue - L08
  • Acne - L70
  • Other follicular disorders - L73
  • Osteomyelitis - M86
  • Acute tubulo-interstitial nephritis - N10
  • Chronic tubulo-interstitial nephritis - N11
  • Cystitis - N30
  • Urethritis and urethral syndrome - N34
  • Inflammatory diseases of prostate - N41
  • Salpingitis and oophoritis - N70
  • Other symptoms and signs involving the digestive system and abdomen - R19
  • Certain early complications of trauma - T79

    Indications and usage:

    To reduce the development of drug-resistant bacteria and maintain the effectiveness of Sulfamethoxazole with Trimethoprim and other antibacterial drugs, Bactrim and Septra should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

  • Urinary tract infections
  • Acute otitis media
  • Acute exacerbations of chronic bronchitis in adults
  • Travelers' diarrhea in adults
  • Shigellosis
  • Pneumocystis jirovecii pneumonia


    Bactrim and Septra are contraindicated in patients with the following:

  • known hypersensitivity to trimethoprim or sulfonamides
  • history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides
  • documented megaloblastic anemia due to folate deficiency
  • pediatric patients less than 2 months of age
  • marked hepatic damage
  • severe renal insufficiency when renal function status cannot be monitored
  • concomitant administration with dofetilide


  • Embryofetal toxicity
  • Hypersensitivity and other serious or fatal reactions
  • Thrombocytopenia
  • Streptococcal infections and rheumatic fever
  • Risk of failure and excess mortality with leucovorin use for pneumocystis jirovecii pneumonia treatment


  • Development of drug resistant bacteria
  • Folate deficiency
  • Hemolysis
  • Hypoglycemia
  • Phenylalanine metabolism
  • Porphyria and hypothyroidism
  • Use in the treatment of and prophylaxis for Pneumocystis jirovecii pneumonia in patients with acquired immunodeficiency syndrome (AIDS)
  • Electrolyte abnormalities



    The amount of a single dose of Septra or Bactrim that is either associated with symptoms of overdosage or is likely to be life-threatening has not been reported. Signs and symptoms of overdosage reported with sulfonamides include anorexia, colic, nausea, vomiting, dizziness, headache, drowsiness, and unconsciousness. Pyrexia, hematuria, and crystalluria may be noted. Blood dyscrasias and jaundice are potential late manifestations of overdosage. Signs of acute overdosage with trimethoprim include nausea, vomiting, dizziness, headache, mental depression, confusion, and bone marrow depression.

    General principles of treatment include the institution of gastric lavage or emesis; forcing oral fluids; and the administration of intravenous fluids if urine output is low and renal function is normal. Acidification of the urine will increase renal elimination of trimethoprim. The patient should be monitored with blood counts and appropriate blood chemistries, including electrolytes. If a significant blood dyscrasia or jaundice occurs, specific therapy should be instituted for these complications. Peritoneal dialysis is not effective and hemodialysis is only moderately effective in eliminating trimethoprim and sulfamethoxazole.


    Use of Sulfamethoxazole and Trimethoprim at high doses and/or for extended periods of time may cause bone marrow depression manifested as thrombocytopenia, leukopenia, and/or megaloblastic anemia. If signs of bone marrow depression occur, the patient should be given leucovorin; 5 to 15 mg leucovorin daily has been recommended by some investigators.

    Drug interactions:

    Potential for Septra and Bactrim to affect other drugs: diuretics, warfarin, phenytoin, methotrexate, cyclosporine, digoxin, indomethacin, pyrimethamine, tricyclic antidepressants (TCAs), oral hypoglycemics, amantadine, angiotensin converting enzyme inhibitors, zidovudine, dofetilide, procainamide.

    Trimethoprim is an inhibitor of CYP2C8 as well as OCT2 transporter. Sulfamethoxazole is an inhibitor of CYP2C9. Caution is recommended when this medication is co-administered with drugs that are substrates of CYP2C8 and 2C9 or OCT2.

    Information for patients:

    Patients should be counseled that antibacterial drugs including Bactrim and Septra should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold). When this medicine is prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may decrease the effectiveness of the immediate treatment and increase the likelihood that bacteria will develop resistance and will not be treatable with sulfamethoxazole/trimethoprim or other antibacterial drugs in the future.

    Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone formation.

    Diarrhea is a common problem caused by antibiotics which usually ends when the antibiotic is discontinued. Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools (with or without stomach cramps and fever) even as late as two or more months after having taken the last dose of the antibiotic. If this occurs, patients should contact their physician as soon as possible.

    Adverse reactions, side effects:

    The most common adverse effects of Bactrim and Septra are gastrointestinal disturbances (nausea, vomiting, anorexia) and allergic skin reactions (such as rash and urticaria). Fatalities associated with the administration of sulfonamides have occurred due to severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms (DRESS), fulminant hepatic necrosis, agranulocytosis, aplastic anemia, other blood dyscrasias, acute and delayed lung injury, anaphylaxis, and circulatory shock.

    Use in specific populations:


    While there are no large, well-controlled studies on the use of trimethoprim and sulfamethoxazole in pregnant women, Brumfitt and Pursell in a retrospective study, reported the outcome of 186 pregnancies during which the mother received either placebo or trimethoprim and sulfamethoxazole. The incidence of congenital abnormalities was 4.5% (3 of 66) in those who received placebo and 3.3% (4 of 120) in those receiving trimethoprim and sulfamethoxazole. There were no abnormalities in the 10 children whose mothers received the drug during the first trimester. In a separate survey, Brumfitt and Pursell also found no congenital abnormalities in 35 children whose mothers had received oral trimethoprim and sulfamethoxazole at the time of conception or shortly thereafter.

    Because trimethoprim and sulfamethoxazole may interfere with folic acid metabolism, Septra or Bactrim should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

    Nursing mothers

    Levels of trimethoprim/sulfamethoxazole in breast milk are approximately 2-5% of the recommended daily dose for infants over 2 months of age. Caution should be exercised when this drug is administered to a nursing woman, especially when breastfeeding jaundiced, ill, stressed, or premature infants because of the potential risk of bilirubin displacement and kernicterus.

    Pediatric use

    This medication is contraindicated for pediatric patients younger than 2 months of age.

    Geriatric use

    Clinical studies of Septra and Bactrim did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.

    Pregnancy categories:

  • C - Australia
  • C - United States (Risk cannot be ruled out)

    Salts and other forms:

  • Sulfamethoxazole Base
  • Sulfamethoxazole Lysine
  • Sulfamethoxazole Sodium
  • Trimethoprim Base
  • Trimethoprim Hydrochloride
  • Trimethoprim Sulfate

    Synonyms, international and chemical names:

  • Cotrimossazolo
  • Cotrimoxazol
  • Co-Trimoxazol
  • Cotrimoxazole
  • Co-Trimoxazole
  • Cotrimoxazolum
  • Co-Trimoxizole
  • Co-Trimoxizolum
  • Ko-Trimoksasool
  • Kotrimoksazol
  • Ko-Trimoksazol
  • Ko-Trimoksazols
  • Kotrimoxazol
  • Ko-Trimoxazol
  • SXT
  • TMPS
  • TMP-Sulfa
  • Trimetoprim / Sulfametoksasool
  • Trimetoprim / Sulfametoksazol
  • Trimetoprim-Sulfametoksazol
  • Trimetoprim-Sulfametoxazol

    Brands, generics, trade names:

  • Abactrim - Roche
  • Anitrim - Italmex
  • Antrima - Abbott
  • Apo-Sulfatrim - Apotex, Hind Wing, Nhan Tam, Pharmaforte
  • Apo-Sulfatrim DS - Apotex
  • Bacfar-F - Elofar Laboratorio Farmaceutico
  • Bacidal - Medichem Pharmaceuticals, United Laboratories
  • Bactelan - Quimica y Farmacia
  • Bactrim - Roche
  • Bactrim-DS - Roche
  • Bactrim-F - Roche
  • Bactrim Forte - Roche, Zuellig Pharma
  • Bactrim Pediatric - Roche, AR Scientific
  • Bactrimel - Roche
  • Bactropin - Cimed Industria de Medicamentos, Son's Laboratorios Quimica
  • Benectrin - EMS Industria Farmaceutica
  • Berlocid - Berlin-Chemie
  • Bioprim - Bioresearch de Mexico, Norma Greece
  • Biseptol - Polfa Pabianice, Medana Pharma, Polfa Warszawa
  • Biseptrim - GlaxoSmithKline
  • Ciplin-DS - Cipla
  • Cotrim - AbZ-Pharma, CT-Arzneimittel, Medochemie, Ratiopharm, Sandoz, Spirig Pharma
  • Cotrim D.S. - Teva, Komedic, Medochemie
  • Cotrim Forte - CT-Arzneimittel, Ratiopharm, Spirig Pharma
  • Cotrim-E - Ratiopharm
  • Cotrim-K - Ratiopharm
  • Cotrimhexal Forte - Hexal
  • Cotrimoxazol - Aliud Pharma, Mipharmco, Sanitas Laboratorio Chimico Farmaceutico
  • Cotrimoxazol Forte - Aliud Pharma, Chile Laboratorios, Sanitas Laboratorio Chimico Farmaceutico
  • Co-Trimoxazol - Akrikhin, Sandoz, Teva
  • Co-Trimoxazol Forte - Helvepharm, Teva
  • Cotrimoxazole - Claris Lifesciences, Ratiopharm, Vatchem-Pharmacy
  • Cotrimoxazole Forte - BOIE
  • Co-Trimoxazole - Mayne Pharma, Pascual Laboratories, Sanavita Pharmaceuticals
  • Cotrimoxazole DS - AstraZeneca
  • CotrimStada - Stada, Khuong Duy Pharmaceutical
  • CotrimStada Forte - Stada
  • DHAtrin - Drug Houses of Australia, U.S. Summit
  • Dientrin - Sanofi-Aventis
  • Diseptyl Forte - Rekah
  • Ectaprim - Liomont Laboratorios
  • Embatrim - Flamingo Pharmaceuticals, Pasteur Pharmaceuticals
  • Embatrim Forte - Flamingo Pharmaceuticals
  • Eusaprim - GlaxoSmithKline
  • Eusaprim Forte - GlaxoSmithKline
  • Globaxol - GX International, Metro Drug Distribution
  • Infectrin - Boehringer Ingelheim
  • Lagatrim - Lagap, Alliance Pharmaceuticals
  • Licoprima - Berlico Mulia Farma
  • Maxtrim - Bristol-Myers Squibb, SSP Laboratories
  • Mediprim - Medika, Switzerland
  • Momentol - Bristol-Myers Squibb
  • Nopil - Mepha, Medimport
  • Nopil Forte - Mepha
  • Novo-Trimel - Novopharm
  • Novo-Trimel DS - Novopharm
  • Nu-Cotrimox - Nu-Pharm
  • Oriprim - Cadila Pharmaceuticals, Zydus Cadila
  • Polibatrin - Teva, IVAX
  • Primadex - Dexa Medica Pharm & Chem
  • Primadex Forte - Dexa Medica Pharm & Chem
  • Primotren - Lek
  • Purbac - Aspen Pharmacare
  • Resprim - Alphapharm, Merck, Serono, Summit, Teva, Zuellig Pharma
  • Resprim Forte - Alphapharm, Teva
  • Sanprima - Sanbe Farma
  • Sepmax - GlaxoSmithKline
  • Septra - GlaxoSmithKline
  • Septra-DS - GlaxoSmithKline, Monarch Pharmaceuticals
  • Septra Pediatric - GlaxoSmithKline
  • Septran - GlaxoSmithKline
  • Septrin - GlaxoSmithKline
  • Septrin Forte - GlaxoSmithKline, Sigma Pharmaceuticals, Zuellig Pharma
  • Septrin Paediatric - GlaxoSmithKline, Zuellig Pharma
  • Septrin-DS - GlaxoSmithKline
  • Septrin-F - GlaxoSmithKline, Sigma Pharmaceuticals
  • Servitrim - Novartis, Sandoz, Servipharm, Zuellig Pharma
  • SMZ-TMP - Bristol-Myers Squibb
  • Soltrim - Almirall, Importadora y Manufacturera Bruluart
  • Sulfamethoprim - Par Pharmaceutical, Quad Pharmaceuticals
  • Sulfamethoxazole, Trimethoprim - Mayne Pharma, Pliva, Sandoz, Sicor Pharmaceuticals, Teva
  • Sulfamethoxazole, Trimethoprim Double Strength - Eon Labs, Mutual Pharmaceuticals, Roxane Laboratories, Teva
  • Sulfatrim - Alpharma, Mekophar Chemical-Pharmaceutical, Superpharm
  • Sulfatrim-DS - Superpharm
  • Sumetrolim - Egis, Medimpex Trading
  • TMS - TAD Pharma, Dr. Grossmann Pharmaca
  • Trimeth / Sulfa - Alpharma, Naska
  • Trimetoprim Sulfa - S.M. Laboratorio Farmaceutico, Fournier, GEA
  • Trimexazol - Sanofi-Aventis, ICN Pharmaceuticals, Valeant Pharmaceuticals
  • Trimezol - Biofarma Farmaceutica
  • Trimoxazole - Sandoz
  • Trisulfa - Jaapharm Canada

    APIs used in medicine in combinations with sulfamethoxazole and trimethoprim:

  • Attapulgite
  • Bromhexine
  • Carbocisteine
  • Cineole
  • Citiolone
  • Dihydrocodeine
  • Erythromycin
  • Guaiacol
  • Guaifenesin
  • Niaouli Oil
  • Peru Balsam
  • Phenylephrine
  • Sulfogaiacol
  • Thenoic Acid

    Here is a list of popular medications containing sulfamethoxazole and trimethoprim as main active pharmaceutical ingredients; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
  • Injectable; Injection; Sulfamethoxazole 400 mg; Trimethoprim 80 mg / 5 ml
  • Suspension; Oral; Sulfamethoxazole 200 mg; Trimethoprim 40 mg / 5 ml
  • Syrup; Oral; Sulfamethoxazole 200 mg; Trimethoprim 40 mg / 5 ml
  • Tablets; Oral; Sulfamethoxazole 100 mg; Trimethoprim 20 mg
  • Tablets; Oral; Sulfamethoxazole 400 mg; Trimethoprim 80 mg
  • Roche
  • Abbott
  • AR Scientific
  • Cenexi
  • Deva Holding
  • DKSH
  • Galenika
  • Investi Farma
  • Mutual Pharmaceuticals
  • Nicholas Piramal
  • Sun Pharmaceutical Industries
  • Teriak Laboratoires Pharmaceutique
  • Zuellig Pharma
  • Bactrim-DS
  • Tablets; Oral; Sulfamethoxazole 800 mg; Trimethoprim 160 mg
  • Roche
  • Abbott
  • AR Scientific
  • Mutual Pharmaceuticals
  • Piramal Healthcare
  • Sun Pharmaceutical Industries
  • Septra
  • Injectable; Injection; Sulfamethoxazole 80 mg; Trimethoprim 16 mg / ml
  • Suspension; Oral; Sulfamethoxazole 200 mg; Trimethoprim 40 mg / 5 ml
  • Tablets; Oral; Sulfamethoxazole 400 mg; Trimethoprim 80 mg
  • GlaxoSmithKline
  • Asiatic Laboratories
  • Aspen Pharmacare
  • Aspri Pharma Canada
  • King Pharmaceuticals
  • Monarch Pharmaceuticals
  • Triton Pharma
  • Septrin
  • Injectable; Injection; Sulfamethoxazole 400 mg; Trimethoprim 80 mg / 5 ml
  • Suspension; Oral; Sulfamethoxazole 200 mg; Trimethoprim 40 mg / 5 ml
  • Tablets; Oral; Sulfamethoxazole 100 mg; Trimethoprim 20 mg
  • Tablets; Oral; Sulfamethoxazole 400 mg; Trimethoprim 80 mg
  • GlaxoSmithKline
  • Alcala Farma Laboratorios
  • Arrow Pharma
  • Aspen
  • Celltech
  • Draxis Health
  • Gerolymatos
  • Jubilant HollisterStier
  • P & D Pharmaceuticals
  • PharmaSwiss
  • PharmaTech
  • Samil Pharmaceutical
  • Sigma Pharmaceuticals
  • UCB Pharma
  • Zuellig Pharma

  • References:

  • Trimethoprim/sulfamethoxazole main article on Wikipedia:
  • Sulfamethoxazole and trimethoprim compound on PubChem:
  • Sulfamethoxazole on DrugBank:
  • Trimethoprim on DrugBank:
  • Co-trimoxazole FAQ on MedlinePlus (revised 10/15/2017):
  • Sulfamethoxazole and Trimethoprim tablets drug label info on DailyMed (revised November 1, 2019):
  • Bactrim DS (Sulfamethoxazole and Trimethoprim) tablets drug label info on DailyMed (revised September 30, 2009):
  • Sulfamethoxazole international drug names on
  • Sulfamethoxazole/Trimethoprim for sale on Pharma Doctor:
  • Sulfamethoxazole containing drugs on
  • Trimethoprim containing drugs on
  • Bactrim (Sulfamethoxazole and Trimethoprim) tablets official prescribing information from the U.S. FDA (revised June 2013):
  • Bactrim (Sulfamethoxazole and Trimethoprim) injection for intravenous use official prescribing and patient counseling information from the U.S. FDA (revised 03/2017):
  • Bactrim DS tablets and Bactrim oral suspension (Sulfamethoxazole and Trimethoprim) consumer medicine information from NPS MedicineWise (revised July 2019):
  • Septra tablets and Septra DS (Sulfamethoxazole and Trimethoprim) official prescribing information from Pfizer pharmaceutical company (revised 12/2020):
  • Septrin (Sulfamethoxazole and Trimethoprim) 400/80 mg and 800/160 mg oral tablets product information from Therapeutic Goods Administration (revised 14 May 2018):
  • Co-trimoxazole tablets 80/400mg (Trimethoprim and Sulfamethoxazole) package information leaflet from (revised December 2020):
  • Co-Trimoxazole Forte 160mg/800mg tablets package information leaflet from (revised March 2020):

    Revised: June 2021